Pfizer Drug Effective In Rare Children Cancers
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The global prevalence of lung cancer in children was estimated to be at least 13.7 cases per million children per year. Lung cancer in children is rare, accounting for only 1–2 percent of childhood cancer cases, but it carries a more ominous prognosis than it does for adults. Most cancer treatments have been developed and tested in adults, and children's cancer conditions are usually treated differently from adults. Patients with lung cancer are often treated with intensive cancer therapy regimes, which can cause adverse effects. This suggests that the risk of side effects for patients taking a drug or vaccine during a public health emergency is less than other patients, and might justify a faster EUA procedure.
As we begin to see the impact of the COVID-19 pandemic on children's cancer treatment, it is important to recognize children's cancer as an important disease and to support efforts to develop and test drugs and vaccines for this population.
The FDA granted a Priority Review Viscosity Quantification (PRVQ) designation to Kodiak Therapeutics Limited. PRVQ is intended to expedite the development of pharmaceuticals to treat cancer. The designation will allow Kodiak to conduct laboratory analyses to better understand the viscosity of its drug candidates and to provide a more robust clinical development plan in order to initiate clinical trials faster.
The FDA granted the orphan drug designation to Epidiolex to facilitate research and development into this treatment. The designation enables the manufacturer to submit an application to the FDA to conduct the clinical trials needed to gain approval for the use of Epidiolex in children.
The FDA is authorizing clinical trials of Epidiolex in adults aged 18 and older. In the United States, the treatment is not approved for use in children under 18. Epidiolex is not approved for use in children in any other countries.
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